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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 45.76
Human Site: Y264 Identified Species: 67.11
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 Y264 V K D S F L L Y M K P D S G A
Chimpanzee Pan troglodytes XP_526380 1125 128795 Y353 V K D S F L L Y M K P D S G A
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 Y264 V K D S F L L Y M K P D S G A
Dog Lupus familis XP_545291 1075 123911 Y264 V K D S F L L Y M K P D S G A
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 Y264 V K D S F L L Y M K P D S G A
Rat Rattus norvegicus P70496 1074 123795 Y264 V K D S F L L Y M K P D S G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 Y262 V K D S F L L Y M K P D S G A
Frog Xenopus laevis NP_001129642 1039 119219 Y265 V K D S F L L Y M K L D T G A
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 Y259 V K D S F L L Y M K P D T G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 Y502 V K E T C F G Y I R P T D G S
Honey Bee Apis mellifera XP_001121004 1135 129725 Y293 V K D T F V A Y I R P K N G S
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 Y439 V R D S F V A Y M D H R T E Q
Sea Urchin Strong. purpuratus XP_784455 790 90080 R95 M K R S G G R R V Q L G C F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 L266 L K P G F L A L L E D P F S G
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 E386 V K E R N V M E K K A E N K P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 100 86.6 93.3 N.A. 33.3 46.6 40 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 93.3 100 N.A. 66.6 86.6 60 40
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 20 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 0 0 0 7 0 0 0 57 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 69 0 0 0 0 0 0 7 7 57 7 0 0 % D
% Glu: 0 0 13 0 0 0 0 7 0 7 0 7 0 7 0 % E
% Phe: 0 0 0 0 75 7 0 0 0 0 0 0 7 7 0 % F
% Gly: 0 0 0 7 7 7 7 0 0 0 0 7 0 69 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % I
% Lys: 0 88 0 0 0 0 0 0 7 63 0 7 0 7 0 % K
% Leu: 7 0 0 0 0 63 57 7 7 0 13 0 0 0 0 % L
% Met: 7 0 0 0 0 0 7 0 63 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 13 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 63 7 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % Q
% Arg: 0 7 7 7 0 0 7 7 0 13 0 7 0 0 0 % R
% Ser: 0 0 0 69 0 0 0 0 0 0 0 0 44 7 19 % S
% Thr: 0 0 0 13 0 0 0 0 0 0 0 7 19 0 0 % T
% Val: 82 0 0 0 0 19 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _